4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole CAS 1356339-86-7

Name: "4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole CAS 1356339-86-7"
Rating: 5 (827 reviews)

جرد:

SKU: 7161032008

الطراز: 4-Bromo-2,6-difluoroaniline 5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-amine 2-Bromo-5-formylpyridine 4-Fluoro-2-methyl-1-isopropyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzimidazole 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

Haohong Pharmaceutical

دخول المتجر

تفاصيل البضائع

Product Summary

This boronic acid ester substituted benzimidazole (CAS 1356339-86-7) is a structurally advanced intermediate for Abemaciclib synthesis. With ≥98% purity and specialized storage under inert gas, it enables precise Suzuki coupling reactions for constructing the drug molecule.

Key Selling Points

Boronate Ester Functionality: Enables efficient Suzuki-Miyaura couplings for Abemaciclib synthesis.
High Purity ≥98% (HPLC): Ensures high reaction yields and low by-product formation.
Inert Gas Storage: Maintains stability and extends shelf life.
Specific Molecular Design: Fluorine and isopropyl groups contribute to the pharmacological properties of the final API.
Custom Synthesis Available: From gram to multi-kilogram quantities.

Technical Specifications

Parameter	Value
CAS Number	1356339-86-7
Appearance	White to off-white solid
Purity	≥98.0% (HPLC)
Storage Conditions	Sealed, inert gas protection, 2–8 °C, avoid light

Models and Options

Available in research and bulk quantities. Custom packaging and COA included.

Materials and Structure

Fluorinated benzimidazole derivative with isopropyl and boronic acid ester groups. This complex structure is essential for late-stage functionalization in Abemaciclib synthesis.

Applications

Pharmaceutical R&D and production, particularly for anti-cancer drugs. Used as a boronic ester intermediate for Abemaciclib API synthesis.

FAQ

What is the purity specification?

≥98% by HPLC analysis.

How is it stored?

Sealed, under inert gas, at 2–8°C, protected from light.

Is it used in Suzuki coupling?

Yes, the boronate ester enables Suzuki reactions.

Can you supply for R&D?

Yes, gram-scale to commercial quantities.

Do you provide COA?

Yes, full batch analysis is provided.

Inquiry Information

Contact Xu Tianxia: Xutx@haohong-pharma.com, +86 180-6854-1569.