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القائمة

N-Methyl-2-Fluoro-4-Bromobenzamide for Apalutamide Intermediate

جرد:
SKU: 5684674437
الطراز: 2-Fluoro-4-nitrobenzoic acid N-Methyl-2-fluoro-4-nitrobenzamide N-Methyl-2-fluoro-4-aminobenzamide N-Methyl-2-fluoro-4-bromobenzamide Methyl 4-bromo-2-fluorobenzoate 5-Amino-3-(trifluoromethyl)pyridinecarbonitrile

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Haohong Pharmaceutical
دخول المتجر
تفاصيل البضائع

N-Methyl-2-Fluoro-4-Bromobenzamide: Apalutamide Intermediate

N-Methyl-2-fluoro-4-bromobenzamide is a halogenated intermediate used in the synthesis of Apalutamide. This white crystalline powder has a purity of ≥98.0% (HPLC) and a melting point of 58–62 °C (estimated). The bromine atom provides a reactive site for cross-coupling reactions in the final synthesis steps.

Key Selling Points

  • High purity (≥98% HPLC): Ensures reliable reactivity and minimal side reactions.
  • Reactive bromine site: Facilitates efficient coupling reactions in Apalutamide synthesis.
  • Stable supply: Backed by our 1000-ton annual production capacity.
  • ICH/GMP compliance: Meets international quality standards for pharmaceutical intermediates.

Technical Specifications

ItemSpecification
CAS Number749927-69-3
Molecular FormulaC₈H₇BrFNO
Molecular Weight232.05
AppearanceWhite crystalline powder
Boiling Point284.8±30 °C
Density1.545±0.06 g/cm³
Purity≥98.0% (HPLC)
StorageSealed, dry, room temperature

Models and Options

Available in bulk quantities with custom packaging; we can supply COA and other documentation.

Materials and Structure

Main material: Bromo-fluoro benzamide organic compound. The bromine and fluorine substituents enable selective functionalization, making it an important intermediate.

Applications

  • Pharmaceutical synthesis, especially anti-cancer drugs.
  • Fine chemical industry.
  • Custom organic synthesis.

Case Study

Our case study shows that this intermediate contributes to high reaction yields and low impurity levels, reducing production costs for clients.

FAQ

What is the purity of this product?≥98.0% (HPLC).
What is the packaging?We offer custom packaging, typically 25kg fiber drums or as requested.
Can you provide samples?Yes, samples are available for evaluation.
What are the shipping terms?We offer EXW, FOB, CIF, and DDP options.
Do you have a certificate of analysis?Yes, COA is provided with every shipment.
Can you support custom synthesis?We provide custom synthesis services ranging from gram to hundreds of kilograms.

Inquiry Information

Contact: Xu Tianxia, Email: Xutx@haohong-pharma.com, Tel: +86 180-6854-1569.

N-Methyl-2-fluoro-4-bromobenzamide white crystalline powder